A mechanism is presented explammg a reported heavy-atom-Induced magnetic field effect as a consequence of nonequihbrmm tnplet sublevel population m an mtermedlate euclplex. The tnplet exclplex spm polanzatlon IS induced by sublevel-selective mtersystem crossmg from the ewlplex trIplet to Its smglet ground state and IS decreased by an external magnetic field. The theory accounts almost quantltat...

The metabolism of sphingomyelin (SPM) was investigated in Epstein-Barr virus-transformed lymphoid cell lines from normal individuals and from patients with Niemann-Pick disease Type A (deficient in the acid, lysosomal sphingomyelinase) and familial hypercholesterolemia (lacking the low density lipoprotein receptor). Cells were incubated with the following radioactive or fluorescent SPMs: [choli...

Spicamycin (SPM), produced by Streptomyces alanosinicus, induces potent differentiation in a human leukemia cell line, HL6O. One of the derivatives of SPM (SPM-D), KRNS500, has a wide range of antltumor activity against human cancer cell lines. We examined the cytotaxicity of SPM-D in small and non-small cell lung cancer cell lines using 3-(4,5dimethylthlazol-2-yl)-2,5-diphenyltefrazoliurn brom...

Objective: To compare the accuracy of SPM and visual analysis of brain SPECT in patients with mesial temporal lobe epilepsy (MTLE). Method: Interictal and ictal SPECTs of 22 patients with MTLE were performed. Visual analysis were performed in interictal (VISUAL(inter)) and ictal (VISUAL(ictal/inter)) studies. SPM analysis consisted of comparing interictal (SPM(inter)) and ictal SPECTs (SPM(icta...

Near infrared spectroscopy (NIRS) is a non-invasive method to measure brain activity via changes in the degree of hemoglobin oxygenation through the intact skull. As optically measured hemoglobin signals strongly correlate with BOLD signals, simultaneous measurement using NIRS and fMRI promises a significant mutual enhancement of temporal and spatial resolutions. Although there exists a powerfu...